Manchester United have been hit hard by injuries in defence, and Ruben Amorim may need an immediate solution to shore up the backline.
Harry Maguire, Leny Yoro and Luke Shaw are injured, while Tyrell Malacia featured for United Under 18s after 17 months of absence.
The Netherlands international will need to accumulate more minutes with the development team before returning to the senior squad.
United’s injury crisis deepened on Saturday when Victor Lindelof was forced off in the 26th minute of the match against Slovakia.
The Swedish defender appeared to suffer a potential hamstring injury while playing as the right centre-back in a back three.
The central defenders will play more minutes under Ruben Amorim, who prefers a 3-4-2-1 formation.
However, limited defensive options could push the new manager to deploy Casemiro in an unfamiliar defensive role.
The £12 million-rated star has been in fine form this campaign, besides his shocking display in the 3-0 loss to Liverpool.
Injuries to Kobbie Mainoo and Christian Eriksen allowed Casemiro to return to the starting XI.
With Manuel Ugarte alongside, Casemiro was not overburdened with the duties of guarding the defence.
The duo could be Amorim’s preferred midfield pairing for the upcoming clash against Ipswich Town on November 24.
However, Casemiro could be shifted to a centre-back role due to injuries mounting in defence.
Eriksen could step in for him in midfield, although concerns remain over his ability to press effectively.
Casemiro could be deployed as the right-sided centre-back or in the middle of the back three.
Amorim asks his players to create a 4-2-2-2 structure when playing out from the back.
The central centre-back often joins the midfield line to create better passing angles and Casemiro would perfectly fit into that role.
Stats from Transfermarkt.com.
