Antonio was forced off after just 20 minutes into his country’s CONCACAF Nations League quarter-final defeat at Independence Park on Saturday.
He immediately went down the tunnel with what appeared to be a hamstring problem but further diagnosis has now revealed that Antonio sustained minor damage to his knee instead.
West Ham initially feared the worst, but Antonio is expected to miss only three weeks of action and could return in December’s League Cup clash against Liverpool.
Nonetheless, the Hammers have been further plunged into an injury crisis in attack with top scorer Jarrod Bowen also currently sidelined.
Despite making a relatively underwhelming start to the season which has seen him score just twice in 12 Premier League games this term, Antonio remains West Ham’s first-choice striker.
In Antonio’s absence, Danny Ings could be set to finally make his first league start of the campaign, although teenage prospect Divin Mubama may also be an option having impressed in pre-season matches against Perth Glory and Tottenham Hotspur.
West Ham currently sit ninth in the Premier League table thanks to a thrilling comeback 3-2 win over Nottingham Forest in their most recent outing before the international break.
They will be looking to pick up consecutive league wins for the first time since September when they visit Turf Moor to face Burnley on Saturday.
- Ratcliffe unable to spend big at Man United this summer due to PSR squeeze
- Fulham ready to offload Palhinha amid Chelsea, Man City & Liverpool interest
- Liverpool eye summer swoop for Crystal Palace defender Marc Guehi
- Premier League calls emergency meeting amid ‘New Deal’ settlement deadline
- Liverpool and Man United table proposals for Kylian Mbappe
- Chelsea poach Brighton recruitment chief Sam Jewell
- Southgate eyes uncapped replacements for struggling Phillips – but are they good enough?
- Should Chelsea try to rescue Kane from Bayern nightmare?
- West Ham shortlist three managers to replace David Moyes
- Ratcliffe to cut around 250 jobs at Man United amid restructuring