A shambolic defensive display saw the visitors concede five goals within the first 21 minutes.
Jacob Murphy and Alexander Isak bagged braces, while Joelinton also got his name on the scoresheet.
Harry Kane’s second-half goal reduced the deficit before Callum Wilson’s 67th-minute strike condemned Spurs to their 11th league defeat this season.
Spurs have endured some absolute hammerings over the years, but Sunday’s defeat was one of their heaviest ever.
We look at three of their biggest losses in the Premier League.
Newcastle 7-1 Tottenham (1996)
Kevin Keegan’s Newcastle team were on a seven-game winless run before Tottenham’s visit to St James’ Park during the 1995-96 season.
However, they bounced back emphatically on their home turf, inflicting Spurs’ heaviest defeat in the Premier League era.
Alan Shearer broke the deadlock after 20 minutes before Les Ferdinand quickly added another by diverting Peter Beardsley’s effort beyond the keeper.
The floodgates opened after the break as Ferdinand and Shearer completed their doubles.
Rob Lee(2) and Philippe Albert also netted as the Magpies won by an emphatic 7-1 scoreline.
Manchester City 6-0 Tottenham (2013)
Tottenham suffered a 6-0 hammering against Manchester City in November 2013, despite the fact they had more possession and only two fewer shots than their rivals.
City were three goals up at the break after an own-goal from Guimaraes Cordeiro either side of strikes from Jesus Navas and Sergio Aguero.
The Argentine forward added another early in the next half before Alvaro Negredo and Navas netted again to seal a famous victory at the Etihad Stadium.
Sheffield United 6-0 Tottenham (1993)
One of Sheffield United’s most memorable victories at Bramall Lane came during the inaugural Premier League campaign against Spurs.
The London outfit were on a five-game winning run, but they were stunned by a breathtaking display from the Blades.
The home side went 4-0 ahead inside the opening half an hour courtesy of Ian Bryson (2), Franz Carr and an Andy Gray own goal.
Brian Deane and Paul Rogers then added two late goals as they registered a superb 6-0 victory.
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